Growth and death kinetics of CHO cells cultivated in continuous bioreactor at various agitation rates
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چکیده
منابع مشابه
Growth and death kinetics of CHO cells cultivated in continuous bioreactor at various agitation rates
Background Mammalian cells are known to be sensitive to hydrodynamic stresses. Therefore, soft agitation and aeration are generally recommended in culture bioreactor to prevent cell damages. Nevertheless, at the industrial scale, this may induce CO2 accumulation, high mixing times, poor air dispersion and concentration gradients. In batch reactor, we have previously found that growth kinetics o...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2011
ISSN: 1753-6561
DOI: 10.1186/1753-6561-5-s8-p101